Teclas de Ayuda de acceso Rápido

ALT + 1 Inicio

ALT + 2 Noticias

ALT + 3 Mapa de sitio

ALT + 4 Búsqueda

ALT + 5 Preguntas frecuentes

ALT + 6 Atención al ciudadano

ALT + 7 Quejas y reclamos

ALT + 8 Iniciar Sesión

ALT + 9 Directorio telefónico

Botones de Accesibilidad

Letra:

Contraste:

Esp
domingo, 20 de octubre 2019
20/10/2019
Síguenos

About the group

Posted Jan 26, 2017

We are interested in understanding numerous aspects of reproduction in mosquito vectors of human disease. Currently, our attention is focused on three mosquito species: Aedes aegypti and Ae. albopictus, the primary vectors of numerous arboviruses that impact human health (including the dengue, chikungunya, and zika viruses) as well as Anopheles albimanus, a major vector of Malaria in Colombia. 

Reproduction is a complex process that involves both a physical interaction between individuals and a molecular interaction between molecules originating from individuals of the opposite sex. A series of behavioral interactions begin during courtship and continue through copulation. Once males and females depart, a molecular interaction continues inside the female between female-specific molecules and substances transferred by males during copulation—sperm, seminal fluid proteins (SFPs) and other small molecules.

Mating induces physiological and behavioral changes in females—collectively referred to as the female post-mating response—that facilitate the production of progeny. In mosquitoes, the female post-mating response includes an increase in host-seeking behaviors, the consumption of a blood-meal, an increase in the rate of egg development, the induction of egg-laying, and an increase in female longevity. Mating also decreases the likelihood that females will re-mate again in their lifetime. These post-mating changes are induced by the receipt of SFPs but may also be influenced by numerous environmental factors.

An additional physiological process mediated by SFPs is the storage of sperm in the female reproductive tract. Once transferred to the females, sperm are stored in specialized organs until they are released to fertilize eggs. Sperm storage is a universal process in species with internal fertilization and is required for fertility. Molecules that mediate sperm storage, such as SFPs and female-specific proteins are key players in fertility and offer potential targets to impact mosquito fertility. However, SFPs and other molecules that mediate female the post-mating responses have not been defined in Aedes aegypti, Aedes albopictus and Anopheles albimanus.

We aim to understand how SFPs, female-specific molecules, and environmental factors influence the fertility of these mosquito vectors. We would like to elucidate sperm storage parameters in mosquitoes and determine how SFPs regulate this important process. As most research has focused on male-derived SFPs in insect fertility, we would like to identify female-specific proteins essential for optimal fertility in mosquitoes. We are also interested in examining how environmental factors, such as the microbiota composition of various tissues, influence the female post-mating response. Finally, we are examining precopulatory behaviors important in successful Anopheles albimanus copuation.

54d4db3244a5e15c6a21152b_logo-renata.png
54d4db5924c957e253bd5fa5_logo-ruana.png
54d4db63ae77e15e6afe94a0_logo-universia.png
54d4db6add1988d75368ecff_logo-icetex.png
54d4db7744a5e15c6a211531_logo-colombiaprende.png
54d4db7edd1988d75368ed05_logo-gobiernolinea.png
54d4db86dd1988d75368ed09_logo-canalu.png
54d4db9644a5e15c6a211534_logo-cis.png
54d4db9d44a5e15c6a211535_logo-colciencias.png
54d4dba444a5e15c6a211539_logo-ips.png
Sistema Único de Información de Trámites - SUIT
54d4dbb7ae77e15e6afe94a4_logo-redemprendia.png
54d4dbbfdd1988d75368ed14_logo-colombia.png
Fundación Universidad de Antioquia
No + filas
No + filas
ORACLE
Hacemos Memoria
Universidad de Antioquia | Vigilada Mineducación | Acreditación institucional hasta el 2022 | NIT 890980040-8
Recepción de correspondencia: calle 70 No. 52 - 21 | Apartado Aéreo 1226 | Dirección: calle 67 No. 53 - 108 | Horario de atención
Conmutador: [57+4] 219 8332 | Línea gratuita de atención al ciudadano: 018000 416384 | Fax: [57+4] 263 8282
Peticiones, quejas, reclamos, sugerencias, denuncias, consultas y felicitaciones
Política de tratamiento de datos personales
Medellín - Colombia | Todos los Derechos Reservados © 2018