Faculty of Pharmaceutical and Food Sciences

Z7_NQ5E12C0LOF160QDKRNCOGGJA1

Research group

Spanish

Marine Natural Products

Academic Unit: Faculty of Pharmaceutical and Food Sciences

Colombian Ministry of Science

A

Call

894 GrupLAC

OECD

Area

Natural sciences

Subarea

Chemical sciences

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Strategic Focus

Our group consists of professionals in chemistry, pharmaceutics, biology, and other closely related disciplines. It aims to develop research projects on the chemistry, biology, and biological activity of Colombian marine natural resources by establishing agreements and networks with other institutions and research groups.

We aim to constitute, along with other Colombian research groups, a research network on marine natural products.

We seek to participate in academic, scientific, and community outreach events.

Research Lines and/or Areas

Marine antiparasitics.
Development of analytical methodologies.
Organic hemisynthesis.
Functional natural products.
Marine antimicrobial natural products.
Chemistry and biological activity of marine natural products.

Sustainable Development Goals (SDGs)

Group Coordinator

Diana Margarita Márquez Fernández, Ph.D.

Ph.D. in Chemical Sciences.

Universidad de Antioquia, Colombia.

Coordinator's Email

diana.marquez@udea.edu.co

Research Group Email

grupomarinos@udea.edu.co

Scientific Cooperation

Collaborative Relationships

Metropolitan Technological Institute.
Universidad Nacional de Colombia, Medellin and Bogota campuses.
Universidad Jorge Tadeo Lozano, Bogota.

University of Catania (Italy).
Federal University of Río de Janeiro (Brazil).

Highlighted Projects

BALCAR-Q: Bioprospection and Chemistry of Caribbean Algae.
Studies on therapeutic coffee-derived polyphenol banks in colorectal cancer in vitro models.
Synthesis of cytarabine conjugates with fatty acids and potentially antitumoral triterpenes, and their interaction with lipid membranes.
Determination of the inhibitory capacity of six epidioxysterol synthetic compounds (analogue to cholesterol) over the replication of Mycobacterium tuberculosis (MTB) in macrophages and in vitro dendritic cells.

Key Research Findings

New Conjugated Compound T5 Epidioxy-Sterol-ANB Inhibits the Growth of Mycobacterium Tuberculosis Affecting the Cholesterol and Folate Pathways. DOI: https://doi.org/10.3389/fmicb.2020.537935
Anomalous interaction of tri-acyl ester derivatives of uridine nucleoside with a l-α-dimyristoylphosphatidylcholine biomembrane model: a differential scanning calorimetry study. DOI: https://doi.org/10.1111/jphp.13038
Anti-Parasite Activity of Novel 3,5-Diiodophenethyl-benzamides. DOI: https://doi.org/10.21577/0103-5053.20180160
DSC studies on the interaction of lipophilic cytarabine prodrugs with DMPC multilamellar vesicles. DOI: https://doi.org/10.1007/s10973-019-08780-x
Synthesis and interaction of sterol-uridine conjugate with DMPC liposomes studied by differential scanning calorimetry. DOI: https://doi.org/10.1016/j.colsurfb.2018.03.023