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In this Master Class, Professor Gloria Cardona will address the challenges and implications of conditions such as dementia and cerebrovascular disorders that affect more and more people in our society. Dementia, characterized by impaired memory, thinking and interpersonal relationships, bears a significant impact on the daily lives of individuals.  "Such alteration affects more than 26 million people worldwide." Latin Americans with dementia will increase from 7 million to 26 million in 2050 (368%), higher than the USA and Europe" (WHO 2021, ADI / BUPA 2020).  

In this chapter, Professor Cardona will talk about how the brain works, how it is shaped and how our habits can deteriorate it. In addition, she will mention the issue of aging as a major risk factor for neurological disorders, such as Alzheimer's disease, the most common type of dementia. As we age, our brain becomes more susceptible to proinflammatory events associated with vascular risk factors and stroke.    

As practitioners and academics, it is critical to address these challenges in a comprehensive manner. In this class, you will learn about prevention strategies, research and the adoption of healthy lifestyles to mitigate the risks associated with dementia and cerebrovascular disorders. And finally, you will learn about the importance of eating a balanced diet, engaging in regular physical activity, and participating in activities that involve social and emotional interaction, as well as resting adequately.

This Master Class is aimed at students and professionals interested in acquiring scientific knowledge and practical strategies to prevent and adopt healthy lifestyles in order to mitigate the risks associated with disorders that affect the brain.

Biography: 

Gloria Patricia Cardona Gómez has been a professor at the Universidad de Antioquia since 2002.  She holds a degree in Biology from the Universidad del Quindío. PhD in Biological Sciences from the Universidad Autónoma de Madrid. Researcher in Cellular and Molecular Neurobiology at the Instituto de Neurobiología Ramón y Cajal in Spain. Senior Researcher at the Neurosciences Group of Antioquia, School of Medicine, Universidad de Antioquia.  

Complementary academic material:   

Books  

• https://www.sciencedirect.com/book/9780128159729/pathology  
• https://www.sciencedirect.com/science/article/abs/pii/B9780128159729000135  
• https://onlinelibrary.wiley.com/doi/book/10.1002/9781119155195  
• https://onlinelibrary.wiley.com/doi/10.1002/9781119155195.ch2  
• https://www.sciencedirect.com/book/9780128179901/factors-affecting-neurological-aging  
• https://www.sciencedirect.com/science/article/abs/pii/B9780128179901000263  

Social appropriation of knowledge    

• https://cuidarmecuidarte.org/como-cuidas-tu-cerebro/  
• https://cuidarmecuidarte.org/micromundo/  

International scientific articles related to the subject  

• Pérez-Corredor PA, Oluwatomilayo-Ojo P, Gutiérrez-Vargas JA, Cardona-Gómez GP. Obesity induces extra cellular vesicle release from the endothelium as a contributor to brain damage after cerebral ischemia in rats. Nutr Neurosci. 2022 Aug 30:1-16. doi: 10.1080/1028415X.2022.2078173. https://www.tandfonline.com/doi/full/10.1080/1028415X.2022.2078173  
• Pérez-Corredor PA, Gutiérrez-Vargas JA, Ciro-Ramírez L, Balcazar N, Cardona-Gómez GP. High fructose diet-induced obesity worsens post-ischemic brain injury in the hippocampus of female rats. Nutr Neurosci. 2022 Jan;25(1):122-136. doi: 10.1080/1028415X.2020.1724453. https://www.tandfonline.com/doi/full/10.1080/1028415X.2020.1724453  
• Patience Ojo O, Perez-Corredor PA, Gutierrez-Vargas JA, Busayo Akinola O, Cardona-Gómez GP. Lasting metabolic effect of a high-fructose diet on global cerebral ischemia. Nutr Neurosci. 2022 Jun;25(6):1159-1172. doi: 10.1080/1028415X.2020.1841482. https://www.tandfonline.com/doi/full/10.1080/1028415X.2020.1841482  
• Villamil-Ortiz JG, Barrera-Ocampo A, Arias-Londoño JD, Villegas A, Lopera F, Cardona-Gómez GP. Differential Pattern of Phospholipid Profile in the Temporal Cortex from E280A-Familiar and Sporadic Alzheimer's Disease Brains. J Alzheimers Dis. 2018;61(1):209-219. doi: 10.3233/JAD-170554. https://content.iospress.com/articles/journal-of-alzheimers-disease/jad170554  
• Villamil-Ortiz JG, Barrera-Ocampo A, Piedrahita D, Velásquez-Rodríguez CM, Arias-Londoño JD, Cardona-Gómez GP. BACE1 RNAi Restores the Composition of Phosphatidylethanolamine-Derivates Related to Memory Improvement in Aged 3xTg-AD Mice. Front Cell Neurosci. 2016 Nov 11;10:260. doi: 10.3389/fncel.2016.00260. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105502/  
• Villamil-Ortiz JG, Cardona-Gomez GP. Comparative analysis of autophagy and tauopathy related markers in cerebral ischemia and Alzheimer's disease animal models. Front Aging Neurosci. 2015 May 19;7:84. doi: 10.3389/fnagi.2015.00084. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436888/  

Keywords:  

Brain, dementia, habits, health, disease, science, life.   

CVLAC:    

https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0000146056   

Contact information:   

patricia.cardonag@udea.edu.co