Faculty of Medicine

Z7_NQ5E12C0LOF160QDKRNCOGGJA1

Research group

Spanish

Cellular and Molecular Biology CIB

Understanding the cellular biology of pathogenic fungi using molecular tools and computational biology.

Evaluation of potential drugs for human use.

Classification of fungi of the genus Aspergillus using classic taxonomy and complete genome sequencing.

Assessment of the presence of possible genes involved in allergic processes and antimicrobial resistance.

Study of cardiovascular diseases using molecular tools.

PhD in Medical Sciences

Universidad Pontificia Bolivariana, Colombia.

Morphological characterization, molecular tipification, and evaluation of the expression of genes involved in the resistance and allergenic protein production of Aspergillus species isolated from in-hospital and out-of-hospital environments in the Aburrá Valley metropolitan area.
Implementation of the CRISPR/Cas9 System for gene editing in fungal pathogens.
Concordance between the estimated biological age with a clinical cardiovascular algorithm and a biomarker-based method.
E. coli expression of Reteplase, a variant of recombinant Human Plasminogen Tissue Activator.

Draft Genome Sequences of Clinical and Environmental Isolates of Aspergillus tamarii from Colombia. DOI: 10.1128/MRA.01514-19
Updates and Comparative Analysis of the Mitochondrial Genomes of Paracoccidioides spp. Using Oxford Nanopore MinION Sequencing. https://doi.org/10.3389/fmicb.2020.01751
Genome analysis reveals evolutionary mechanisms of adaptation in systemic dimorphic fungi. ISSN 2045-2322. DOI: 10.1038/s41598-018-22816-6
Molecular Epidemiology of Candida auris in Colombia Reveals a Highly Related, Countrywide Colonization With Regional Patterns in Amphotericin B Resistance. DOI: 10.1093/cid/ciy411

Technical services for the assessment of possible molecules or antimicrobial drugs, mainly for fungi and bacteria.
Expert advice on bioinformatic analysis (microorganisms).