School of Microbiology

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Research group

Spanish

Molecular Hematopathology

Academic Unit: School of Microbiology

Colombian Ministry of Science

C

Call

894 GrupLAC

OECD

Area

Medical and health sciences

Subarea

Clinical medicine

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Strategic Focus

The Molecular Hematopathology Group (HEMO Group) of the School of Microbiology of the Universidad de Antioquia, through the study of the different blood components and the application of new technologies, proposes the development of research lines in the area of hematology. This is done to promote basic and applied research and, at the same time, to make the generation of knowledge and the formation of human resources possible at an undergraduate and graduate level. Strategic Lines: Physiology and Hematic Pathology: Alterations in hemostasis: Immunohematology and blood bank:

Research Lines and/or Areas

Hematic physiology and pathology.
Alterations in hemostasis.
Immunohematology and blood bank.

Sustainable Development Goals (SDGs)

Group Coordinator

Paola Andrea Acevedo Toro, MSc

Master's Degree in Microbiology. Emphasis Hematology.

School of Microbiology Universidad de Antioquia – Colombia.

Coordinator's Email

paola.acevedo@udea.edu.co

Scientific Cooperation

Collaborative Relationships

Academic and research partnerships: UNIGEM, Dinámica - SURA, School of Microbiology blood bank, Biocientifica Ltda y Hemociencia, Mindray.

Highlighted Projects

Methylation analysis in patients with chronic myeloid leukemia in different medical institutions of Medellin.
Characterization of B-cell monoclonal lymphocytosis in relatives of patients with chronic lymphoid leukemia and its relation to demographic and biological variables.
Behavior of serum hepcidin in donors who attend the blood bank and in patients with disorders related to iron metabolism who attend the IPS University clinic León XIII, Medellin, 2013.
Mutations profile in coagulation Factors V and II and in methyltetrahydrofolate reductase in patients with thrombophilia treated in IPS Dinámica in Medellin between 2017-2018.
Frequency of mutations in the genes JAK2, MPL and CALR in chronic myeloproliferative neoplasms bcr/abl negative of different institutions in the city of Medellin.
Analysis of mutations in coagulation factors II and V and in methyltetrahydrofolate reductase in patients with thrombophilia treated at Dinámica IPS in Medellin.

Key Research Findings

The Molecular Hematopathology Group is a pioneer in the determination of the hepcidin molecule, which is important in the evaluation of some hematological disorders in which iron metabolism is affected. With this project, the group won a second place for the best research by the Asociación Colombiana de Hemato Oncología (Colombian Association of Hemato-Oncology).
Among other projects with social impact that were awarded by the Colegio Nacional de Bacteriólogos (National College of Bacteriologists), we highlight isoimmunization screening of umbilical cord samples from neonates assisted at a fourth level of complexity clinic in eastern Antioquia.
ACOBASMET 2020 Silver Award FOR RESEARCH. Is it necessary to complement coombs direct results with elution in erythrocyte isoimmunization research?

Services and/or Products Portfolio

Haematological Consultancy Service: This service supports the morphological review and correct interpretation of the hemoleucogram to provide an accurate diagnosis and quality assurance of some hematological and non-hematological diseases. Some examples of them are anemias, acute and chronic leukemias, lymphomas, myelodysplastic syndromes, multiple myeloma, and mononucleoside syndrome.